Characterization and comparison of invasive Corynebacterium diphtheriae isolates from France and Poland.
نویسندگان
چکیده
Corynebacterium diphtheriae, the agent of diphtheria, is rarely responsible for bacteremia. However, high numbers of bacteremia have been reported in countries with extensive immunization coverage. Here, we used molecular and phenotypic tools to characterize and compare 42 invasive isolates collected in France (including New Caledonia) and Poland over a 23-year period.
منابع مشابه
Characterization and comparison of invasive Corynebacterium diphtheriae isolates from France
Running title: Invasive Corynebacterium diphtheriae 3 E. Farfour, E. Badell, A. Zasada, H. Hotzel, H. Tomaso, S. Guillot and N. Guiso 4 5 1 Institut Pasteur, Unité Prévention et Thérapies Moléculaires des Maladies Humaines, National 6 Reference Centre of Toxigenic Corynebacteria, 7 2 CNRS-URA 3012 8 3 National Institute of Public Heath National Institute of Hygiene, Department of Bacteriology, ...
متن کاملInfluenza vaccine-induced interstitial lung disease.
typing identifies evidence for recombination and two distinct lineages of Corynebacterium diphtheriae. J Clin Microbiol 2010; 48: 4177– 4185. 3 Wagner KS, White JM, Lucenko I, et al. Diphtheria in the postepidemic period, Europe, 2000–2009. Emerg Infect Dis 2012; 18: 217–225. 4 Wilson AP. The return of Corynebacterium diphtheriae: the rise of nontoxigenic strains. J Hosp Infect 1995; 30: Suppl....
متن کاملChanges in MLST profiles and biotypes of Corynebacterium diphtheriae isolates from the diphtheria outbreak period to the period of invasive infections caused by nontoxigenic strains in Poland (1950–2016)
BACKGROUND Corynebacterium diphtheriae is a re-emerging pathogen in Europe causing invasive infections in vaccinated persons and classical diphtheria in unvaccinated persons. In the presented study we analysed genetic changes in C. diphtheriae isolates collected in Poland from the period before the introduction of the mass anti-diphtheria vaccination to the present time when over 98% of the pop...
متن کاملEmergence of related nontoxigenic Corynebacterium diphtheriae biotype mitis strains in Western Europe.
We report on 17 isolates of Corynebacterium diphtheriae biotype mitis with related ribotypes from Switzerland, Germany, and France. Isolates came from skin and subcutaneous infections of injecting drug users, homeless persons, prisoners, and elderly orthopedic patients with joint prostheses or primary joint infections. Such isolates had only been observed in Switzerland.
متن کاملHuman clinical isolates of Corynebacterium diphtheriae and Corynebacterium ulcerans collected in Canada from 1999 to 2003 but not fitting reporting criteria for cases of diphtheria.
A 5-year collection of Corynebacterium diphtheriae and Corynebacterium ulcerans human clinical isolates yielded nine isolates from blood cultures of patients with invasive infections, stressing the importance of C. diphtheriae as a serious blood-borne pathogen. Seven percent of C. diphtheriae and 100% of C. ulcerans isolates produced diphtheria toxin, demonstrating that toxigenic corynebacteria...
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ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 50 1 شماره
صفحات -
تاریخ انتشار 2012